Gordon Freeman, hero of Half-Life, is that you?
This is Freeman as he appears on the box art for 2006's Half-Life 2 in 2004. There hasn't been a new Half-Life game since 2007, despite fans' frequent please to series' creator Valve Software to make a new one.
Gordon, it's nice to see you again... sort of.
I don't watch Breaking Bad (I know, I know... I should). I'm guessing that there's no actual Half-Life crossover in the show.
As for this poster, others people appear to have noticed this earlier this month. I didn't catch it until this week, when the posters started going up at stations for Manhattan and Brooklyn's worst subway line, the C train.