The good news is for PC users. Bioware expects a reasonably fast fix for some CD key rejection issues. A BioWare QA lead said that an installer had been sent out as of Wednesday evening, but had no ETA for its approval. "We haven't been able to talk to the people who are processing it though so we're not sure what the status is. I'm hoping it will be on the store soonish."
The bad news is for 360 gamers. The problem seems to be with the Platinum Hits version of the game. Owners of that are asked to reroll their character to play - which shouldn't happen. Some reported that buying the Bring Down the Sky DLC - again - resolved the problem, and they're super pissed and demanding refunds. The BioWare QA guy popped in to say they were aware of the problem but had no ETA for any fixes.