In an interview with Official Nintendo Magazine, the Level 5 CEO Akihiro Hino has said the studio has no plans to bring Professor Layton to the Wii, despite the series' strong popularity on the DS.
Hino said the current trilogy will close out with "Professor Layton and the Last Time Travel", and a new one will open with "Professor Layton and the Flute of Malevolent Destiny", to be released in Japan.
"The new trilogy will also be based around solving puzzles, but will also include greatly improved bonus modes so I think that players will be able to enjoy the games for even longer. We currently have no plans for a Wii release," Hino told ONM. So, there ya go.