Fallout 3 introduced us to the Ink Spots and 1941's "I Don't Want to Set the World on Fire". Fallout: New Vegas opens here with Kay Kyser's. "Jingle Jangle Jingle", the No. 1 hit for eight weeks in 1942.
That's about the only useful thing I can add to this two-minute video, slam full of gameplay, heralding New Vegas's appearance at E3 2010. It speaks for itself, and I advise you to listen. And watch.