In a Famitsu interview, translated by 1up Eiji Aonuma revealed a few more details about The Legend of Zelda: Skyward Sword. For those extremely wary of spoilers, you may want to watch your step here.
First and foremost - this time round, apparently Zelda is not a princess.
"She's not a princess this time," claimed Aonuma, "which is something I'll pretty much have to put forth right now in order to talk about this title. She's a childhood friend, but she goes away in the midst of the game and it's Link's job to search for her.
"This game's plot is something like a school drama, you could say. The flying sequence at the E3 demo is Link competing against his classmates. One of them looks kind of a like a bad guy, as you saw, and he shows up in other ways in the game too, since he has a major thing for Zelda."
In addition to certain shake ups with how the plot unfolds, both Miyamoto and Aonuma decided to play around with items, in an attempt to make Zelda less of a traditional, familiar experience.
"With previous Zeldas," stated Aonuma, "the common pattern was that the really neat items wouldn't show up until later on in the game. You need to have the basic item set or it wouldn't be Zelda, so the new items tended to get shunted to the latter part of the game. [Shigeru]Miyamoto said that had to change, like 'This is neat, let's bring it out from the start.' So a lot of neat new items will show up pretty early on."
For a few more details, including information on the new hub world, check out the 1up translation here.