One of the things that impressed me most about the 3DS was its online. With the 3DS, Nintendo has delivered a solid online experience -- an experience that will be M.I.A. for Monster Hunter 3G.
It is possible to get online with Monster Hunter 3DS to do things like download event quests. You just won't be able to play with your faraway buddies.
The game's Wii version did support online; however, the 3DS version will not. Instead, players can connect via ah hoc wireless play. Old school.