When I look at iconic manga and anime Akira, I don't immediately think of Bart Simpson and Milhouse. Cartoonist James Harvey does.
Harvey is spearheading the "Bartkira" project. It's a group project that consists of over 300 artists, all working in their own styles. Below you can see the cast of characters:
As Harvey explains: "Some aspects of the cast list might be surprising, but I’m confident that you’ll see the logic and consideration that went into the choices I ended up making when you read the book. Believe me, I went through nearly every reasonable combination of characters and this roster works the best, in terms of character motivation and interaction."
This is a "free-wheeling" project, but, eventually, the goal seems to be completing all six volumes (over 2000 pages!) of the Akira manga.