Maybe there's a little Borderlands in there for good measure too. Comparisons aside, Tower of Guns is a twitch shooter with roguelike elements that hope to keep every playthrough fresh.
This means random enemies, random powerups, random bosses, many unlockables and even random levels every time you play. Excellent.
From the game's Steam Greenlight page:
CRAZY POWERUPS: You've played first person shooters where you can double jump, but have you played any game where you can centuple-jump? You can in Tower of Guns, with the right items.
GUN-MODIFYING MADNESS: A gun and its qualities aren't tied together in Tower of Guns. Do you like rocket launchers? You'll like them more if you're lucky enough to stumble upon a "shotgun" modifier. A rocket-launching shotgun is very satisfying.
OLD-SCHOOL TACTICS: For the fans of the faster shooters, it's all back: circle strafing, bunny hopping, rocket jumping. Tower of Guns is all about moving fast!
OLD-SCHOOL LEVEL DESIGN: Hate invisible blocking walls that keep you from exploring a cool vista? I do. They're outlawed in Tower of Guns. If you can see it, you can get to it...if you have the right items.
It may just be that this combines two of my favourite genres -- shooters and roguelikes -- but I for one am excited to play this. According to Rock Paper, Shotgun, the game will be out "sometime before the next Thief game". The developer wants to be able to play Thief without guilt, which I guess means being finished with Tower of Guns first. For now, you can vote for the game on Steam Greenlight.