Just because they're fictional characters doesn't mean we can't care about them -- obviously, everyone knows that. But there are reasons that that's true, you know! Scientific reasons, even.
PBS Game/Show explains why we sometimes deeply care about game characters here, and then even lists some of their favourite non-playable characters in games. Makes me curious -- what are some of your favourite NPCs? Why do you like them so much?
My top two would have to be Morrigan from Dragon Age (she is a strong, complicated character with an agenda of her own) and basically the entire cast of Persona 4 (WAAAAH WE ATE WATERMELON TOGETHER AND SAVED THE WORLD WITH FRIENDSHIP).
What about you?