Supervillain teams are destined to fail, whether it's Carnage and his team of villains, Doctor Doom and whoever he was able to force to join, or — in this case — the Sinister Six. With their ego, it just cannot work. Here's Dorkly's piece about the mathematical law of Superhero film villains.
Hopefully the Sinister Six will be a lot more badass in the next Spider-Man movie:
Check out more Dorkly comics over here.