Jack Bauer will play Naked Snake in Metal Gear Solid V: The Phantom Pain, Konami just announced during its pre-recorded E3 press conference. Naked Snake, as you might remember from MGS3, is actually Big Boss, clone-father to longtime series protagonist Solid Snake. But this is a big twist for the series: all incarnations of Snake are usually played by the gravelly voiced David Hayter.
Kiefer Sutherland, best known for his role as super-agent Bauer in the show 24, will do motion capturing and voice work for the new Metal Gear game, which takes place after the upcoming Metal Gear Solid: Ground Zeroes (and way before the events of Metal Gear Solid IV).
You can see video footage of the Sutherland announcement above.