Perhaps not in terms of its core mechanics -- although they may change too -- but the above teaser, which takes the form of an actually-quite-informative documentary, seems to indicate a shift in the themes of Call of Duty, switching its focus away from the idea of fighting for your country to the idea of Private Military Contractors and the commercialisation of war.
It's instantly made me at least 50% more interested in the next Call of Duty.
This mini-documentary has been created in partnership with Vice, who do some top-notch video content. Apparently it's essentially a shrunken down version of a longer investigation by Vice which I'm keen to watch.
If this sort of thematic content makes it into the game, I think it could be interesting. The Call of Duty series has always had a pretty straight-laced American-goodies vs the terrorist-baddies storyline. This has the potential to shake things up a bit.
Apparently the next Call of Duty will be revealed on 4 May. So we'll find out a bit more then.