For a game that was one of the killer apps for the Xbox 360, it's surprising the PC version never shipped with proper controller support. Leave it to modders then to do the work of BioWare and Microsoft by cramming it in there post-launch. Or should I say post-post-post-launch, seeing as the game came out in 2010.
So you can play Mass Effect 2 with a gamepad. That's kind of exciting, but perhaps not mind-blowing. Well, this mod also adds the power wheel from the console version, so it's extremely faithful to its Xbox One counterpart as a control method.
The modification can be found over on the ME3 Explorer forums, though it should be mentioned it requires a small tweak to get working. It involves using a save editor to map a power to the "Y" button, but it's not heinously complicated to do.
If you're wondering about the other two Mass Effect games, the news is good -- this mod will serve as a foundation for including controller support in those titles also, though you'll have to be patient.